Yes. From NConstruct version 2.5 you can choose to use WCF web services instead of .NET remoting. This option can be set through NConstruct Builder wizard...

...or later in the generated solution:

For more information, please refer to the following articles:
-
NConstruct v2.5 - Breaking Changes -
NConstruct & WCF Web Services Hosting in IIS
_______________________
NConstruct Support Team
support@nconstruct.comhttp://www.nconstruct.com_______________________